Research protocol version 2.4 dt. 25JULY2023

Pocket card

Checklist

Huisartsenbrief

Informed consent forms / information letter

• Belgium
• Netherlands

CRFs on paper

24 hrs _5_7days follow up

90 day_FUunblinded

Baseline

CRF paper worksheets all combined

Deferred treatment

Discharge form

Discharge intervention center

Discharge second hospital (transfer)

Endovascular treatment

Inclusion and exclusion

SAE form

Study treatment

Standard Operating Procedure

SOP clinical follow-up by telephone at 3 months in the CASES trial

SOP patient information and deferred consent (CASES)

SOP randomization follow-up and data collection (CASES)

SOP Imaging upload